DNAH2 facilitates the homologous recombination repair of Fanconi anemia pathway through modulating FANCD2 ubiquitination

DNAH2 facilitates the homologous recombination repair of Fanconi anemia pathway through modulating FANCD2 ubiquitination

Abstract. Fanconi anemia (FA), an X-linked genetic or autosomal recessive disease, exhibits complicated pathogenesis. Previously, we detected the mutated Dynein Axonemal Heavy Chain 2 (DNAH2) gene in 2 FA cases. Herein, we further investigated the potential association between DNAH2 and the homologo...

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Main Authors: Lixian Chang, Xingjie Gao, Yuxia Wang, Chunmin Huang, Min Gao, Xiaomin Wang, Chao Liu, Wenqi Wu, Wenbin An, Yang Wan, Aoli Zhang, Yingchi Zhang, Weiping Yuan, Xiaofan Zhu
Format: Article
Language:English
Published: Wolters Kluwer Health 2021-07-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000076

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http://journals.lww.com/10.1097/BS9.0000000000000076

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