Integrated 16S rDNA sequencing and metabolomics to explore the intestinal changes in children and rats with dental fluorosis

Integrated 16S rDNA sequencing and metabolomics to explore the intestinal changes in children and rats with dental fluorosis

Dental fluorosis (DF) is a widely prevalent disease caused by excessive fluoride with limited awareness of its underlying pathogenesis. Here, a pilot population study was conducted to explore the pathogenesis of DF from the perspective of intestinal microbiome changes, and verified it in animal expe...

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Bibliographic Details
Main Authors: Guoyu Zhou, Qingyuan Li, Xiangbo Hou, Huiying Wu, Xiaoli Fu, Guoqing Wang, Jun Ma, Xuemin Cheng, Yang Yang, Ruiqin Chen, Zhiyuan Li, Fangfang Yu, Jingyuan Zhu, Yue Ba
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Dental Fluorosis
Microorganism
Metabolite
Pentose and glucuronate interconversion pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323000222

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http://www.sciencedirect.com/science/article/pii/S0147651323000222

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