CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

Summary: Inflammatory responses are crucial for controlling infections and initiating tissue repair. However, excessive and uncontrolled inflammation causes inflammatory disease. Processing and release of the pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18 depend on caspase-1 activation...

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Bibliographic Details
Main Authors: Savita Devi, Mohanalaxmi Indramohan, Elisabeth Jäger, Jessica Carriere, Lan H. Chu, Lucia de Almeida, David R. Greaves, Christian Stehlik, Andrea Dorfleutner
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723002760

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http://www.sciencedirect.com/science/article/pii/S2211124723002760

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