Significance and implications of FHIT gene expression and promoter hypermethylation in acute lymphoblastic leukemia (ALL)

Significance and implications of FHIT gene expression and promoter hypermethylation in acute lymphoblastic leukemia (ALL)

Abstract Background Fragile histidine triad (FHIT) has been documented to play a vital role in various cancers including acute lymphoblastic leukemia (ALL). Keeping in view the plausible role of FHIT gene, we aimed to examine DNA promoter hypermethylation and mRNA expression in ALL cases in Kashmir...

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Bibliographic Details
Main Authors: Fozia Mohammad, Arshad A. Pandith, Shayaq Ul Abeer Rasool, Faisal R. Guru, Iqbal Qasim, Sajad Geelani, Syed Nisar, Shahid M. Baba, Farooq A. Ganie, Safiya Kouser, Javid Rasool
Format: Article
Language:English
Published: Springer 2024-04-01
Series:Discover Oncology
Subjects:
Acute lymphoblastic leukemia
FHIT expression
FHIT gene hypermethylation
B-cell ALL
mRNA expression
Online Access:https://doi.org/10.1007/s12672-024-00971-9

Internet

https://doi.org/10.1007/s12672-024-00971-9

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