Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats

Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats

Homocysteine is a sulfur-containing endogenous amino acid leading to neurotoxic effects at high concentrations. Population studies suggest an association between plasma homocysteine levels and the risk of migraine headaches. The aim of this study was to analyze the sensitivity of rats with prenatal...

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Bibliographic Details
Main Authors: Elena Gerasimova, Olga Yakovleva, Daniel Enikeev, Ksenia Bogatova, Anton Hermann, Rashid Giniatullin, Guzel Sitdikova
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
migraine
hyperhomocysteinemia
nitroglycerine
allodynia
anxiety
photophobia
Online Access:https://www.mdpi.com/2218-273X/12/5/735

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https://www.mdpi.com/2218-273X/12/5/735

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