Identifying response and predictive biomarkers for Transcranial magnetic stimulation outcomes: protocol and rationale for a mechanistic study of functional neuroimaging and behavioral biomarkers in veterans with Pharmacoresistant depression

Identifying response and predictive biomarkers for Transcranial magnetic stimulation outcomes: protocol and rationale for a mechanistic study of functional neuroimaging and behavioral biomarkers in veterans with Pharmacoresistant depression

Abstract Background Although repetitive transcranial magnetic stimulation (‘TMS’) is becoming a gold standard treatment for pharmacoresistant depression, we lack neural target biomarkers for identifying who is most likely to respond to TMS and why. To address this gap in knowledge we evaluate neural...

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Bibliographic Details
Main Authors: Leanne M. Williams, John T. Coman, Patrick C. Stetz, Nicole C. Walker, F. Andrew Kozel, Mark S. George, Jong Yoon, Laura M. Hack, Michelle R. Madore, Kelvin O. Lim, Noah S. Philip, Paul E. Holtzheimer
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Psychiatry
Subjects:
Major depressive disorder (MDD)
Treatment resistant depression (TRD)
Repetitive Transcranial magnetic stimulation (TMS)
Dorsolateral prefrontal cortex (DLPFC)
Functional magnetic resonance imaging (fMRI)
Neuroimaging
Online Access:https://doi.org/10.1186/s12888-020-03030-z

Internet

https://doi.org/10.1186/s12888-020-03030-z

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