Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis
The aim of this study was to evaluate the effectiveness of the combination of resistance training (RT) and protein supplementation (PS), compared to RT alone or combined with a placebo (plS), in the improvement of muscle strength and physical performance. The search strategy in PubMed, Cochrane Libr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/9/2607 |
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| author | Noé Labata-Lezaun Luis Llurda-Almuzara Carlos López-de-Celis Jacobo Rodríguez-Sanz Vanessa González-Rueda César Hidalgo-García Borja Muniz-Pardos Albert Pérez-Bellmunt |
| author_facet | Noé Labata-Lezaun Luis Llurda-Almuzara Carlos López-de-Celis Jacobo Rodríguez-Sanz Vanessa González-Rueda César Hidalgo-García Borja Muniz-Pardos Albert Pérez-Bellmunt |
| author_sort | Noé Labata-Lezaun |
| collection | DOAJ |
| description | The aim of this study was to evaluate the effectiveness of the combination of resistance training (RT) and protein supplementation (PS), compared to RT alone or combined with a placebo (plS), in the improvement of muscle strength and physical performance. The search strategy in PubMed, Cochrane Library, and Web of Sciences databases found a total of 294 studies. Once inclusion and exclusion criteria were applied, 16 studies were included for the qualitative analysis. A total of 657 healthy elderly (>60 years) participants were analysed. Finally, 15 articles were included in the quantitative analysis with one being excluded due to issues with data availability. Upper-limb, lower-limb, and handgrip strength were the primary outcomes of the meta-analysis. The secondary outcomes, related to physical performance, were Short Physical Performance Battery (SPPB), gait speed, and the five-chair-rise test (5CRT). The main results of the meta-analysis show no statistical differences for upper-limb (SMD: 0.56, 95% CI: −0.09, 1.21, <i>p</i> = 0.09, I2 = 68%), lower-limb (SMD: 0.00, 95% CI: −0.18, 0.18, <i>p</i> = 1.0, I2 = 11%), and handgrip strength (SMD: 0.03, 95% CI: −0.26, 0.32, <i>p</i> = 0.84, I2 = 0%) between the RT + PS and the RT alone (or combined with plS). Moreover, no statistical differences were found relating to physical performance. In view of these results, protein supplementation combined with RT does not provide additional benefits compared to RT alone or with plS in healthy elderly adults. |
| first_indexed | 2024-03-10T16:46:42Z |
| format | Article |
| id | doaj.art-3574d1a1ab054cf4b9e1420b9e1b35fc |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T16:46:42Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-3574d1a1ab054cf4b9e1420b9e1b35fc2023-11-20T11:32:10ZengMDPI AGNutrients2072-66432020-08-01129260710.3390/nu12092607Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-AnalysisNoé Labata-Lezaun0Luis Llurda-Almuzara1Carlos López-de-Celis2Jacobo Rodríguez-Sanz3Vanessa González-Rueda4César Hidalgo-García5Borja Muniz-Pardos6Albert Pérez-Bellmunt7Department of Basic Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Barcelona, SpainDepartment of Basic Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Barcelona, SpainPhysiotherapy Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Barcelona, SpainDepartment of Basic Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Barcelona, SpainPhysiotherapy Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Barcelona, SpainPhysiotherapy Department, Faculty of Health Sciences, Universidad de Zaragoza, 50009 Zaragoza, SpainGENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, 50009 Zaragoza, SpainDepartment of Basic Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Barcelona, SpainThe aim of this study was to evaluate the effectiveness of the combination of resistance training (RT) and protein supplementation (PS), compared to RT alone or combined with a placebo (plS), in the improvement of muscle strength and physical performance. The search strategy in PubMed, Cochrane Library, and Web of Sciences databases found a total of 294 studies. Once inclusion and exclusion criteria were applied, 16 studies were included for the qualitative analysis. A total of 657 healthy elderly (>60 years) participants were analysed. Finally, 15 articles were included in the quantitative analysis with one being excluded due to issues with data availability. Upper-limb, lower-limb, and handgrip strength were the primary outcomes of the meta-analysis. The secondary outcomes, related to physical performance, were Short Physical Performance Battery (SPPB), gait speed, and the five-chair-rise test (5CRT). The main results of the meta-analysis show no statistical differences for upper-limb (SMD: 0.56, 95% CI: −0.09, 1.21, <i>p</i> = 0.09, I2 = 68%), lower-limb (SMD: 0.00, 95% CI: −0.18, 0.18, <i>p</i> = 1.0, I2 = 11%), and handgrip strength (SMD: 0.03, 95% CI: −0.26, 0.32, <i>p</i> = 0.84, I2 = 0%) between the RT + PS and the RT alone (or combined with plS). Moreover, no statistical differences were found relating to physical performance. In view of these results, protein supplementation combined with RT does not provide additional benefits compared to RT alone or with plS in healthy elderly adults.https://www.mdpi.com/2072-6643/12/9/2607elderlyresistance trainingprotein supplementationmuscle strengthphysical performance |
| spellingShingle | Noé Labata-Lezaun Luis Llurda-Almuzara Carlos López-de-Celis Jacobo Rodríguez-Sanz Vanessa González-Rueda César Hidalgo-García Borja Muniz-Pardos Albert Pérez-Bellmunt Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis Nutrients elderly resistance training protein supplementation muscle strength physical performance |
| title | Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis |
| title_full | Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis |
| title_fullStr | Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis |
| title_short | Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis |
| title_sort | effectiveness of protein supplementation combined with resistance training on muscle strength and physical performance in elderly a systematic review and meta analysis |
| topic | elderly resistance training protein supplementation muscle strength physical performance |
| url | https://www.mdpi.com/2072-6643/12/9/2607 |
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