Real-Time Monitoring the Effect of Cytopathic Hypoxia on Retinal Pigment Epithelial Barrier Functionality Using Electric Cell-Substrate Impedance Sensing (ECIS) Biosensor Technology

Real-Time Monitoring the Effect of Cytopathic Hypoxia on Retinal Pigment Epithelial Barrier Functionality Using Electric Cell-Substrate Impedance Sensing (ECIS) Biosensor Technology

Disruption of retinal pigment epithelial (RPE barrier integrity is a hallmark feature of various retinal blinding diseases, including diabetic macular edema and age-related macular degeneration, but the underlying causes and pathophysiology are not completely well-defined. One of the most conserved...

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Bibliographic Details
Main Authors: Michael H. Guerra, Thangal Yumnamcha, Abdul-Shukkur Ebrahim, Elizabeth A. Berger, Lalit Pukhrambam Singh, Ahmed S. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
age related macular degeneration (AMD)
diabetic macular edema (DME)
cytopathic hypoxia
retinal pigment epithelial cells (RPE)
ARPE-19
CoCl<sub>2</sub>
Online Access:https://www.mdpi.com/1422-0067/22/9/4568

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https://www.mdpi.com/1422-0067/22/9/4568

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