Isolation of feline islets of Langerhans by selective osmotic shock produces glucose responsive islets

Isolation of feline islets of Langerhans by selective osmotic shock produces glucose responsive islets

IntroductionPancreatic islet isolation is essential for studying islet physiology, pathology, and transplantation, and feline islets could be an important model for human type II diabetes mellitus (T2D). Traditional isolation methods utilizing collagenases inflict damage and, in cats, may contribute...

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Bibliographic Details
Main Authors: Lauren T. Porter, Christopher A. Adin, Chiquitha D. Crews, Jocelyn Mott, Chen Gilor
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Veterinary Science
Subjects:
diabetes mellitus
islet isolation
feline
GLUT2
selective osmotic shock
β-cell
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1365611/full

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https://www.frontiersin.org/articles/10.3389/fvets.2024.1365611/full

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