A co-ordinated transcriptional programme in the maternal liver supplies long chain polyunsaturated fatty acids to the conceptus using phospholipids

Abstract The long and very long chain polyunsaturated fatty acids (LC-PUFAs) are preferentially transported by the mother to the fetus. Failure to supply LC-PUFAs is strongly linked with stillbirth, fetal growth restriction, and impaired neurodevelopmental outcomes. However, dietary supplementation...

Full description

Bibliographic Details
Main Authors: Risha Amarsi, Samuel Furse, Mary A. M. Cleaton, Sarah Maurel, Alice L. Mitchell, Anne C. Ferguson-Smith, Nicolas Cenac, Catherine Williamson, Albert Koulman, Marika Charalambous
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51089-z