7-(1-Methyl-3-Pyrrolyl-)-4,6-Dinitrobenzofuroxan Reduces the Frequency of Antibiotic Resistance Mutations Induced by Ciprofloxacin in Bacteria

7-(1-Methyl-3-Pyrrolyl-)-4,6-Dinitrobenzofuroxan Reduces the Frequency of Antibiotic Resistance Mutations Induced by Ciprofloxacin in Bacteria

The aim of the present study was to investigate biological properties of the novel nitrobenzoxadiazole derivative 7-(1-methyl-3-pyrrolyl-)-4,6-dinitrobenzofuroxan. Materials and Methods: We used a bioluminescent test based on a set of lux-biosensors, which are genetically modified E.coli strains ab...

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Bibliographic Details
Main Authors: Vladimir A. Chistyakov, Evgeniya V. Prazdnova, Evgeniya Y. Kharchenko, Sergey V. Kurbatov, Mikhail M. Batiushin, Ekaterina S. Levitskaya, Maria S. Mazanko, Mikhail N. Churilov
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2016-09-01
Series:International Journal of Biomedicine
Subjects:
antibioitic resistance
fluoroquinolones
SOS-response
SOS-inhibitors
nitrobenzoxadiazole derivatives
antimutagens
Online Access:http://ijbm.org/articles/IJBM_6(3)_OA15.pdf

Internet

http://ijbm.org/articles/IJBM_6(3)_OA15.pdf

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