Inactivation of the MAPK signaling pathway by Listeria monocytogenes infection promotes trophoblast giant cell death

Inactivation of the MAPK signaling pathway by Listeria monocytogenes infection promotes trophoblast giant cell death

Listeria monocytogenes has a well-characterized ability to cross the placental barrier, resulting in spontaneous abortion and fetal infections. However, the mechanisms resulting in infection-associated abortion are not fully understood. In this study, we demonstrate that the dephosphorylation of MAP...

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Bibliographic Details
Main Authors: Masanori eHashino, Masato eTachibana, Takashi eNishida, Hideki eHara, Kohsuke eTsuchiya, Masao eMitsuyama, Kenta eWatanabe, Takashi eShimizu, Masahisa eWatarai
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Microbiology
Subjects:
Infection
Listeria monocytogenes
Placenta
Abortion
MAPK
trophoblast
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01145/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01145/full

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