Studying the Interactions of U24 from HHV-6 in Order to Further Elucidate Its Potential Role in MS

Studying the Interactions of U24 from HHV-6 in Order to Further Elucidate Its Potential Role in MS

A number of studies have suggested that human herpesvirus 6A (HHV-6A) may play a role in multiple sclerosis (MS). Three possible hypotheses have been investigated: (1) U24 from HHV-6A (U24-6A) mimics myelin basic protein (MBP) through analogous phosphorylation and interaction with Fyn-SH3; (2) U24-6...

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Bibliographic Details
Main Authors: Keng-Shuo Pi, Daria Bortolotti, Yurou Sang, Giovanna Schiuma, Silvia Beltrami, Sabrina Rizzo, Alessandra Bortoluzzi, Eleonora Baldi, A. Louise Creagh, Charles A. Haynes, Roberta Rizzo, Suzana K. Straus
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
human herpes virus
<i>Roseolovirus</i>
Fyn-SH3
Nedd4L
multiple sclerosis
phosphorylation
Online Access:https://www.mdpi.com/1999-4915/14/11/2384

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https://www.mdpi.com/1999-4915/14/11/2384

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