Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasion

Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasion

Abstract Background ST6GALNAC family members function as sialyltransferases and have been implicated in cancer progression. However, their aberrant expression levels, prognostic values and specific roles in metastatic prostate cancer (PCa) remain largely unclear. Methods Two independent public datas...

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Bibliographic Details
Main Authors: Meiqian Li, Zhihui Ma, Yuqing Zhang, Hanyi Feng, Yang Li, Weicong Sang, Rujian Zhu, Ruimin Huang, Jun Yan
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Cancer Cell International
Subjects:
Prostate cancer
Metastasis
ST6GALNAC5
GATA2
Prognostic biomarker
Online Access:https://doi.org/10.1186/s12935-023-02983-x

Internet

https://doi.org/10.1186/s12935-023-02983-x

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