Effect of oxaliplatin plus 5-fluorouracil or capecitabine on circulating and imaging biomarkers in patients with metastatic colorectal cancer: a prospective biomarker study

Effect of oxaliplatin plus 5-fluorouracil or capecitabine on circulating and imaging biomarkers in patients with metastatic colorectal cancer: a prospective biomarker study

Abstract Background Patients with metastatic colorectal cancer are treated with cytotoxic chemotherapy supplemented by molecularly targeted therapies. There is a critical need to define biomarkers that can optimise the use of these therapies to maximise efficacy and avoid unnecessary toxicity. Howev...

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Bibliographic Details
Main Authors: Reem D. Mahmood, Danielle Shaw, Tine Descamps, Cong Zhou, Robert D. Morgan, Saifee Mullamitha, Mark Saunders, Nerissa Mescallado, Alison Backen, Karen Morris, Ross A. Little, Susan Cheung, Yvonne Watson, James P. B. O’Connor, Alan Jackson, Geoff J. M. Parker, Caroline Dive, Gordon C. Jayson
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Angiogenesis
Biomarkers
Bevacizumab
Online Access:https://doi.org/10.1186/s12885-021-08097-9

Internet

https://doi.org/10.1186/s12885-021-08097-9

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