Advances in the Development of SARS-CoV-2 Mpro Inhibitors

Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find inhibitors of the main protease (Mpro) of the virus SARS-CoV-2. Initially, previously reported inhibitors of related proteases such as the main proteases of SARS-CoV and MERS-CoV were tested. A huge e...

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Bibliographic Details
Main Authors: Laura Agost-Beltrán, Sergio de la Hoz-Rodríguez, Lledó Bou-Iserte, Santiago Rodríguez, Adrián Fernández-de-la-Pradilla, Florenci V. González
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/8/2523