High Antiproliferative Activity of Hydroxythiopyridones over Hydroxypyridones and Their Organoruthenium Complexes

High Antiproliferative Activity of Hydroxythiopyridones over Hydroxypyridones and Their Organoruthenium Complexes

Hydroxypyr(id)ones are a pharmaceutically important class of compounds that have shown potential in diverse areas of drug discovery. We investigated the 3-hydroxy-4-pyridones <b>1a</b>–<b>1c</b> and 3-hydroxy-4-thiopyridones <b>1d</b>–<b>1f</b> as well...

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Bibliographic Details
Main Authors: Md. Salman Shakil, Shahida Parveen, Zohaib Rana, Fearghal Walsh, Sanam Movassaghi, Tilo Söhnel, Mayur Azam, Muhammad Ashraf Shaheen, Stephen M. F. Jamieson, Muhammad Hanif, Rhonda J. Rosengren, Christian G. Hartinger
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
3-hydroxy-4-pyridone
3-hydroxy-4-thiopyridone
anticancer agents
apoptosis
cytotoxicity
Ru(arene) complexes
Online Access:https://www.mdpi.com/2227-9059/9/2/123

Internet

https://www.mdpi.com/2227-9059/9/2/123

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