Interferon gene therapy with nadofaragene firadenovec for bladder cancer: from bench to approval

Bladder cancer is a prevalent malignancy with limited therapeutic options, particularly for patients who are unresponsive to Bacillus Calmette-Guérin (BCG). The approval of interferon-α (IFNα) gene therapy with nadofaragene firadenovec (Adstiladrin®), the first gene therapy for genitourinary maligna...

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Bibliographic Details
Main Authors: Alberto Martini, Côme Tholomier, Sharada Mokkapati, Colin P. N. Dinney
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1260498/full