Assessment of syndecan-4 expression in the hearts of Trypanosoma cruzi-infected mice and human subjects with chronic Chagas disease cardiomyopathy

Assessment of syndecan-4 expression in the hearts of Trypanosoma cruzi-infected mice and human subjects with chronic Chagas disease cardiomyopathy

Abstract Background Chronic Chagas cardiomyopathy (CCC) is characterized by the presence of a multifocal inflammatory response and myocardial damage, leading to fibrosis, arrhythmias and ventricular dysfunction. The expression of syndecan-4, a transmembrane proteoglycan, was previously found to be i...

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Bibliographic Details
Main Authors: Ticiana Ferreira Larocca, Bruno Solano de Freitas Souza, Carolina Thé Macêdo, Carine Machado Azevedo, Juliana Fraga Vasconcelos, Daniela Nascimento Silva, Diogo Crispim Nascimento Portella, Washington Luis Conrado dos Santos, Fabio Rocha Fernandes Tavora, João David de Souza Neto, Ricardo Ribeiro dos Santos, Milena Botelho Pereira Soares
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Surgical and Experimental Pathology
Subjects:
Syndecan-4
Chagas disease
Cardiomyopathy
Online Access:http://link.springer.com/article/10.1186/s42047-018-0012-9

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http://link.springer.com/article/10.1186/s42047-018-0012-9

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