IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle

IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle

Mitochondrial NADP<sup>+</sup>-dependent isocitrate dehydrogenase (IDH2) catalyzes the oxidative decarboxylation of isocitrate into α-ketoglutarate with concurrent reduction of NADP<sup>+</sup> to NADPH. However, it is not fully understood how IDH2 is intertwined with muscle...

Full description

Bibliographic Details
Main Authors:	Jeong Hoon Pan, Jingsi Tang, Young Jun Kim, Jin Hyup Lee, Eui-Cheol Shin, Jiangchao Zhao, Kee-Hong Kim, Kyung A. Hwang, Yan Huang, Jae Kyeom Kim
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	International Journal of Molecular Sciences
Subjects:	IDH2 knockout skeletal muscle myogenesis mitochondrial biogenesis fatty acid oxidation UCP1
Online Access:	https://www.mdpi.com/1422-0067/21/16/5596

Similar Items

Histone variants in skeletal myogenesis
by: Nandini Karthik, et al.
Published: (2021-03-01)

Angiogenesis precedes myogenesis during regeneration following biopsy injury of skeletal muscle
by: Nicole L. Jacobsen, et al.
Published: (2023-02-01)

The wasting‐associated metabolite succinate disrupts myogenesis and impairs skeletal muscle regeneration
by: Paige C. Arneson‐Wissink, et al.
Published: (2020-07-01)

The Role of Mitophagy in Skeletal Muscle Damage and Regeneration
by: Eirini Chatzinikita, et al.
Published: (2023-02-01)

Network visualization of genes involved in skeletal muscle myogenesis in livestock animals
by: Fatemeh Mohammadi Nejad, et al.
Published: (2024-03-01)

The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis
by: Manoel L. Costa, et al.
Published: (2021-05-01)

DBC1 maintains skeletal muscle integrity by enhancing myogenesis and preventing myofibre wasting
by: Na Liang, et al.
Published: (2024-02-01)

Circular RNA Regulation of Myogenesis
by: Pengpeng Zhang, et al.
Published: (2019-08-01)

Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432
by: Shanshan Wang, et al.
Published: (2022-12-01)

Progressive Alteration of UCP and ANT in Skeletal Muscle of Fasted Chickens
by: Masaaki Toyomizu, et al.
Published: (2006-06-01)

Decapeptide from Potato Hydrolysate Induces Myogenic Differentiation and Ameliorates High Glucose-Associated Modulations in Protein Synthesis and Mitochondrial Biogenesis in C2C12 Cells
by: Yi-Ju Chen, et al.
Published: (2022-04-01)

Ginsenoside Rf Enhances Exercise Endurance by Stimulating Myoblast Differentiation and Mitochondrial Biogenesis in C2C12 Myotubes and ICR Mice
by: Won-Chul Lim, et al.
Published: (2022-06-01)

Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
by: Lampros Mavrommatis, et al.
Published: (2023-11-01)

Exercise-induced PGC-1α transcriptional factors in skeletal muscle
by: Suryun Jung, et al.
Published: (2014-12-01)

Non-Coding RNA Regulates the Myogenesis of Skeletal Muscle Satellite Cells, Injury Repair and Diseases
by: Yue Zhao, et al.
Published: (2019-08-01)

Regulation of myogenic cell proliferation and differentiation during mammalian skeletal myogenesis
by: Jiyao Wu, et al.
Published: (2024-05-01)

Ishige okamurae and diphloroethohydoxycarmalol inhibit palmitic acid-impaired skeletal myogenesis and improve muscle regenerative potential
by: Thilina U. Jayawardena, et al.
Published: (2021-12-01)

The Effect of either Aerobic Exercise Training or Chrysin Supplementation on Mitochondrial Biogenesis in Skeletal Muscle of High Fat Diet-Induced Obese Mice
by: Kyung-Il Kim, et al.
Published: (2019-11-01)

Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle
by: Pieter A. Leermakers, et al.
Published: (2020-01-01)

Beyond antioxidants: Selenium and skeletal muscle mitochondria
by: Lauren T. Wesolowski, et al.
Published: (2022-12-01)

Dermatopontin in Skeletal Muscle Extracellular Matrix Regulates Myogenesis
by: Taeyeon Kim, et al.
Published: (2019-04-01)

Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration
by: Min-Kyoung Shin, et al.
Published: (2022-05-01)

Mechanisms and effects of metformin on skeletal muscle disorders
by: Ren Shang, et al.
Published: (2023-10-01)

Stage-specific effects of Notch activation during skeletal myogenesis
by: Pengpeng Bi, et al.
Published: (2016-09-01)

Astaxanthin improves skeletal muscle regeneration in CTX-induced injury of HFD-fed obese mice via mitochondrial biogenesis
by: Mengting Chen, et al.
Published: (2024-04-01)

Oncogenetic landscape and clinical impact of IDH1 and IDH2 mutations in T-ALL
by: Mathieu Simonin, et al.
Published: (2021-05-01)

A Circular RNA Generated from Nebulin (NEB) Gene Splicing Promotes Skeletal Muscle Myogenesis in Cattle as Detected by a Multi‐Omics Approach
by: Kongwei Huang, et al.
Published: (2024-01-01)

Electrospun Poly(L-lactide-co-ε-caprolactone) Scaffold Potentiates C2C12 Myoblast Bioactivity and Acts as a Stimulus for Cell Commitment in Skeletal Muscle Myogenesis
by: Serafina Pacilio, et al.
Published: (2023-02-01)

Reduced satellite cell density and myogenesis in Wagyu compared with Angus cattle as a possible explanation of its high marbling
by: X. Fu, et al.
Published: (2018-01-01)

Mitochondrial biogenesis is decreased in skeletal muscle of pig fetuses exposed to maternal high-energy diets
by: T.D. Zou, et al.
Published: (2017-01-01)

Transcription Factor Movement and Exercise-Induced Mitochondrial Biogenesis in Human Skeletal Muscle: Current Knowledge and Future Perspectives
by: Dale F. Taylor, et al.
Published: (2022-01-01)

Implications for the mammalian sialidases in the physiopathology of skeletal muscle
by: Fanzani Alessandro, et al.
Published: (2012-11-01)

Expression profiles of muscle disease-associated genes and their isoforms during differentiation of cultured human skeletal muscle cells
by: Abdul-Hussein Saba, et al.
Published: (2012-12-01)

Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors
by: In Young Choi, et al.
Published: (2020-02-01)

Chchd10 is dispensable for myogenesis but critical for adipose browning
by: Wei Xia, et al.
Published: (2022-04-01)

Systematic Myostatin Expression Screening Platform for Identification and Evaluation of Myogenesis-Related Phytogenic in Pigs
by: Bor-Rung Ou, et al.
Published: (2023-09-01)

The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways
by: L. Coudert, et al.
Published: (2021-07-01)

Role of Actin-Binding Proteins in Skeletal Myogenesis
by: Mai Thi Nguyen, et al.
Published: (2023-10-01)

Activin A Causes Muscle Atrophy through MEF2C-Dependent Impaired Myogenesis
by: Audrey Loumaye, et al.
Published: (2022-03-01)

Pitx2 in Embryonic and Adult Myogenesis
by: Amelia E. Aranega, et al.
Published: (2017-05-01)