The effect of BCG vaccination on infection and antibody levels against SARS-CoV-2—The results of ProBCG: a multicenter randomized clinical trial in Brazil

ABSTRACT: Objectives: Evatuate if Bacillus Calmette-Guérin (BCG) vaccine could be used as a tool against SARS-CoV-2 based on the concept of trained immunity. Methods: A multicenter, double-blinded, randomized clinical trial recruited health care workers (HCWs) in Brazil. The incidence rates of COVI...

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Main Authors: Ana Paula Santos, Guilherme Loureiro Werneck, Ana Paula Razal Dalvi, Carla Conceição dos Santos, Paulo Fernando Guimarães Morando Marzocchi Tierno, Hanna Silva Condelo, Bruna Macedo, Janaina Aparecida de Medeiros Leung, Jeane de Souza Nogueira, Ludmila Malvão, Rafael Galliez, Roberta Aguiar, Roberto Stefan, Sabrina Modena Knackfuss, Elisangela Costa da Silva, Terezinha Marta Pereira Pinto Castineiras, Roberto de Andrade Medronho, José Roberto Lapa e Silva, Rogério Lopes Rufino Alves, Luís Cristóvão de Moraes Sobrino Porto, Luciana Silva Rodrigues, Afrânio Lineu Kritski, Fernanda Carvalho de Queiroz Mello
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223000656