The Human Disease-Associated Aβ Amyloid Core Sequence Forms Functional Amyloids in a Fungal Adhesin

ABSTRACT There is increasing evidence that many amyloids in living cells have physiological functions. On the surfaces of fungal cells, amyloid core sequences in adhesins can aggregate into 100- to 1,000-nm-wide patches to form high-avidity adhesion nanodomains on the cell surface. The nanodomains f...

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Bibliographic Details
Main Authors: Rachele D. Rameau, Desmond N. Jackson, Audrey Beaussart, Yves F. Dufrêne, Peter N. Lipke
Format: Article
Language:English
Published: American Society for Microbiology 2016-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01815-15