Single Sustained Inflation followed by Ventilation Leads to Rapid Cardiorespiratory Recovery but Causes Cerebral Vascular Leakage in Asphyxiated Near-Term Lambs.

A sustained inflation (SI) rapidly restores cardiac function in asphyxic, bradycardic newborns but its effects on cerebral haemodynamics and brain injury are unknown. We determined the effect of different SI strategies on carotid blood flow (CaBF) and cerebral vascular integrity in asphyxiated near-...

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Bibliographic Details
Main Authors: Kristina S Sobotka, Stuart B Hooper, Kelly J Crossley, Tracey Ong, Georg M Schmölzer, Samantha K Barton, Annie R A McDougall, Suzie L Miller, Mary Tolcos, Claus Klingenberg, Graeme R Polglase
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4713062?pdf=render