Neurocircuitry underlying the antidepressant effect of retrograde facial botulinum toxin in mice

Abstract Backgrounds Botulinum toxin type A (BoNT/A) is extensively applied in spasticity and dystonia as it cleaves synaptosome-associated protein 25 (SNAP25) in the presynaptic terminals, thereby inhibiting neurotransmission. An increasing number of randomized clinical trials have suggested that g...

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Bibliographic Details
Main Authors: Linhui Ni, Hanze Chen, Xinxin Xu, Di Sun, Huaying Cai, Li Wang, Qiwen Tang, Yonggang Hao, Shuxia Cao, Xingyue Hu
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-023-00964-1