Blood-stage antiplasmodial activity and oocyst formation-blockage of metallo copper-cinchonine complex

Blood-stage antiplasmodial activity and oocyst formation-blockage of metallo copper-cinchonine complex

In the fight against malaria, the key is early treatment with antimalarial chemotherapy, such as artemisinin-based combination treatments (ACTs). However, Plasmodium has acquired multidrug resistance, including the emergence of P. falciparum strains with resistance to ACT. The development of novel a...

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Bibliographic Details
Main Authors: Camila Martins Gomes Morais, Ramayana Morais de Medeiros Brito, Aleksandra Weselucha-Birczyńska, Valeska Santana de Sena Pereira, Jordam William Pereira-Silva, Alexandre Menezes, Felipe Arley Costa Pessoa, Martyna Kucharska, Malwina Birczyńska-Zych, Claudia María Ríos-Velásquez, Valter Ferreira de Andrade-Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium
malaria treatment
cinchonine
mettalo copper complexes
antimalarial drugs
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1047269/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1047269/full

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