Tripartite motif 38 attenuates cardiac fibrosis after myocardial infarction by suppressing TAK1 activation via TAB2/3 degradation

Tripartite motif 38 attenuates cardiac fibrosis after myocardial infarction by suppressing TAK1 activation via TAB2/3 degradation

Summary: The role of tripartite motif (TRIM) 38, a ubiquitin E3 ligase regulating various pathophysiological processes, in cardiac fibrosis remains unclear. Here, a model of angiotensin II and myocardial infarction (MI)-induced fibrosis was established to explore its role in cardiac fibrosis and its...

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Bibliographic Details
Main Authors: Zhengri Lu, Chunshu Hao, Hao Qian, Yuanyuan Zhao, Xiangwei Bo, Yuyu Yao, Genshan Ma, Lijuan Chen
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
cardiovascular medicine
pathophysiology
cell biology
functional aspects of cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010525

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http://www.sciencedirect.com/science/article/pii/S2589004222010525

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