IRESpy: an XGBoost model for prediction of internal ribosome entry sites

Abstract Background Internal ribosome entry sites (IRES) are segments of mRNA found in untranslated regions that can recruit the ribosome and initiate translation independently of the 5′ cap-dependent translation initiation mechanism. IRES usually function when 5′ cap-dependent translation initiatio...

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Bibliographic Details
Main Authors: Junhui Wang, Michael Gribskov
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2999-7