Contributions of chaperone and glycosyltransferase activities of <it>O</it>-fucosyltransferase 1 to Notch signaling
<p>Abstract</p> <p>Background</p> <p><it>O</it>-fucosyltransferase1 (OFUT1) is a conserved ER protein essential for Notch signaling. OFUT1 glycosylates EGF domains, which can then be further modified by the <it>N</it>-acetylglucosaminyltransferas...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-01-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/6/1 |