Role of the TWEAK-Fn14-cIAP1-NF-kB signaling axis in the regulation of myogenesis and muscle homeostasis

Mammalian skeletal muscle maintains a robust regenerative capacity throughout life, due largely to the presence of a stem cell population known as satellite cells in the muscle milieu. In normal conditions, these cells remain quiescent; they are activated upon injury to become myoblasts, which proli...

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Bibliographic Details
Main Authors: Emeka K Enwere, Nadine eAdam, Eric C LaCasse, Robert G Korneluk
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00034/full