Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon
Abstract The oxoglutarate dehydrogenase complex (OGDHc) participates in the tricarboxylic acid cycle and, in a multi-step reaction, decarboxylates α-ketoglutarate, transfers succinyl to CoA, and reduces NAD+. Due to its pivotal role in metabolism, OGDHc enzymatic components have been studied in isol...
| Príomhchruthaitheoirí: | , , , , , , , , , , , |
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| Formáid: | Alt |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
Nature Portfolio
2023-05-01
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| Sraith: | Communications Biology |
| Rochtain ar líne: | https://doi.org/10.1038/s42003-023-04885-0 |