Unraveling the landscapes and regulation of scanning, leaky scanning, and 48S initiation complex conformations
Summary: Scanning and initiation are critical steps in translation. Here, we utilized translation complex profiling (TCP-seq) to investigate 48S organization and eIF4G1-eIF1 inhibition impact. We provide global views of scanning and leaky scanning, uncovering a central role of eIF4G1-eIF1 in their r...
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| 格式: | 文件 |
| 语言: | English |
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Elsevier
2024-05-01
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| 丛编: | Cell Reports |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S2211124724004546 |