Adjunctive rosiglitazone treatment for severe pediatric malaria: A randomized placebo-controlled trial in Mozambican children

Adjunctive rosiglitazone treatment for severe pediatric malaria: A randomized placebo-controlled trial in Mozambican children

Objectives: We tested the hypothesis that adjunctive rosiglitazone treatment would reduce levels of circulating angiopoietin-2 (Angpt-2) and improve outcomes of Mozambican children with severe malaria. Methods: A randomized, double-blind, placebo-controlled trial of rosiglitazone vs placebo as adjun...

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Bibliographic Details
Main Authors: Rosauro Varo, Valerie M. Crowley, Humberto Mucasse, Antonio Sitoe, Justina Bramugy, Lena Serghides, Andrea M. Weckman, Clara Erice, Rubao Bila, Pio Vitorino, Campos Mucasse, Marta Valente, Sara Ajanovic, Núria Balanza, Kathleen Zhong, Yiovanna Derpsch, Melissa Gladstone, Alfredo Mayor, Quique Bassat, Kevin C. Kain
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:International Journal of Infectious Diseases
Subjects:
Adjunctive
Treatment
Plasmodium falciparum
Malaria
Severe
Rosiglitazone
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223007920

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http://www.sciencedirect.com/science/article/pii/S1201971223007920

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