An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)

An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)

Positron emission tomography (PET) with 18F-PM-PBB3 (18F-APN-1607, 18F-Florzolotau) enables high-contrast detection of tau depositions in various neurodegenerative dementias, including Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). A simplified method for quantifying rad...

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Bibliographic Details
Main Authors: Kenji Tagai, Yoko Ikoma, Hironobu Endo, Oiendrila Bhowmik Debnath, Chie Seki, Kiwamu Matsuoka, Hideki Matsumoto, Masaki Oya, Kosei Hirata, Hitoshi Shinotoh, Keisuke Takahata, Shin Kurose, Yasunori Sano, Maiko Ono, Hitoshi Shimada, Kazunori Kawamura, Ming-Rong Zhang, Yuhei Takado, Makoto Higuchi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:NeuroImage
Subjects:
Tau PET
Reference tissues
Alzheimer's disease
Progressive supranuclear palsy
Frontotemporal lobar degeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811922008849

Internet

http://www.sciencedirect.com/science/article/pii/S1053811922008849

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