Synthesis and hypoglycemic activity of quinoxaline derivatives

In this study, a new series of quinoxalinone derivatives (5a–5p, 6a–6n) was designed and its hypoglycemic activity was evaluated. The results showed that compounds 5i and 6b exhibited stronger hypoglycemic effects than the lead compounds and were comparable to the positive control Pioglitazone. 5i a...

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Bibliographic Details
Main Authors: Weidong Jia, Jingjing Wang, Chengxi Wei, Ming Bian, Shuyin Bao, Lijun Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1197124/full