Calcium Sensing Receptors Mediate Local Inhibitory Reflexes Evoked by L-Phenylalanine in Guinea Pig Jejunum

Calcium Sensing Receptors Mediate Local Inhibitory Reflexes Evoked by L-Phenylalanine in Guinea Pig Jejunum

Amino acids applied to the mucosa evoke inhibitory reflexes in guinea-pig jejunum, but the receptors involved in sensory transduction are still unclear. One promising candidate is the extracellular calcium sensing receptor (CaSR), which is expressed by mucosal enteroendocrine cells and is preferenti...

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Bibliographic Details
Main Authors: Rachel M. Gwynne, Kenny D. K. N. Ly, Laura J. Parry, Joel C. Bornstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Physiology
Subjects:
extracellular CaSR
L-Phenylalanine
L-glutamate
inhibitory reflexes
ATP
5-HT
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00991/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00991/full

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