A biomimetic electrostatic assistance for guiding and promoting N-terminal protein chemical modification

Phosphorylation is a mechanism used by cells to promote proteins-biomolecules association. Here, the authors show the effect of the interactions between proteins equipped with positively charged arginines and peptides harbouring negatively charged phosphoserines, enabling rate acceleration and chemi...

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Bibliographic Details
Main Authors: Nathalie Ollivier, Magalie Sénéchal, Rémi Desmet, Benoît Snella, Vangelis Agouridas, Oleg Melnyk
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34392-5