The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells

The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells

Abstract Background Graphene oxide (GO) nanoparticles (NPs) have been widely applied in various fields, especially in biomedical applications. Extensive studies have suggested that GO can pass through the blood–brain barrier (BBB) and induce abnormal autophagy and cytotoxicity in the central nervous...

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Bibliographic Details
Main Authors: Chao Zhang, Xiaoli Feng, Longwen He, Yaqing Zhang, Longquan Shao
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Nanobiotechnology
Subjects:
Graphene oxide
Astrocyte
p62
Autophagy
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12951-020-00605-6

Internet

http://link.springer.com/article/10.1186/s12951-020-00605-6

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