AG73-GelMA/AlgMA hydrogels provide a stable microenvironment for the generation of pancreatic progenitor organoids

AG73-GelMA/AlgMA hydrogels provide a stable microenvironment for the generation of pancreatic progenitor organoids

Abstract Patient specific induced pluripotent stem cells (iPSCs) derived β cells represent an effective means for disease modeling and autologous diabetes cell replacement therapy. In this study, an AG73-5%gelatin methacryloyl (GelMA) /2% alginate methacrylate (AlgMA) hydrogel was employed to genera...

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Bibliographic Details
Main Authors: Jian Wan, Yang Xu, Tianmu Qi, Xiaoxia Xue, Yuxi Li, Minjie Huang, Yuchen Guo, Qingsong Guo, Yuhua Lu, Yan Huang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Nanobiotechnology
Subjects:
GelMA/AlgMA hydrogel
Induced pluripotent stem cells
Organoids
Differentiation
Diabetes
Online Access:https://doi.org/10.1186/s12951-025-03266-5

Internet

https://doi.org/10.1186/s12951-025-03266-5

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