Insulin-like growth factor 1 receptor and response to anti-IGF1R antibody therapy in osteosarcoma.

Insulin-like growth factor 1 receptor and response to anti-IGF1R antibody therapy in osteosarcoma.

Survival outcomes for patients with osteosarcoma (OS) have remained stagnant over the past three decades. Insulin-like growth factor 1 receptor (IGF1R) is over-expressed in a number of malignancies, and anti-IGF1R antibodies have and are currently being studied in clinical trials. Understanding the...

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Bibliographic Details
Main Authors: Yu Cao, Michael Roth, Sajida Piperdi, Kristofer Montoya, Rebecca Sowers, Pulivarthi Rao, David Geller, Peter Houghton, E Anders Kolb, Jonathan Gill, Richard Gorlick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149550?pdf=render

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http://europepmc.org/articles/PMC4149550?pdf=render

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