Exposure to Deoxynivalenol During Pregnancy and Lactation Enhances Food Allergy and Reduces Vaccine Responsiveness in the Offspring in a Mouse Model

Exposure to Deoxynivalenol During Pregnancy and Lactation Enhances Food Allergy and Reduces Vaccine Responsiveness in the Offspring in a Mouse Model

Deoxynivalenol (DON), a highly prevalent contaminant of grain-based products, is known to induce reproductive- and immunotoxicities. Considering the importance of immune development in early life, the present study investigated the effects of perinatal DON exposure on allergy development and vaccine...

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Bibliographic Details
Main Authors: Negisa Seyed Toutounchi, Saskia Braber, Belinda van’t Land, Suzan Thijssen, Johan Garssen, Aletta D. Kraneveld, Gert Folkerts, Astrid Hogenkamp
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
Deoxynivalenol
developmental immunotoxicity
food allergy
vaccination
pregnancy
lactation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.797152/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.797152/full

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