Randomized, double-blind, placebo-controlled study to evaluate the effect of treatment with an SPMs-enriched oil on chronic pain and inflammation, functionality, and quality of life in patients with symptomatic knee osteoarthritis: GAUDI study

Randomized, double-blind, placebo-controlled study to evaluate the effect of treatment with an SPMs-enriched oil on chronic pain and inflammation, functionality, and quality of life in patients with symptomatic knee osteoarthritis: GAUDI study

Abstract Background Specialized pro-resolving mediators (SPMs), including 18-HEPE, 17-HDHA, and 14-HDHA are recognized as potentially therapeutic in inflammatory diseases because SPMs regulate the inflammation process, which leads to, for example; swelling and the sensation of pain. In osteoarthriti...

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Bibliographic Details
Main Authors: Ingrid Möller, Gil Rodas, Jose María Villalón, Jose A. Rodas, Francisco Angulo, Nina Martínez, Josep Vergés
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Translational Medicine
Subjects:
Specialized pro-resolving mediators
SPMs
Resolvins
Supplementation
Osteoarthritis
Chronic pain
Online Access:https://doi.org/10.1186/s12967-023-04283-4

Internet

https://doi.org/10.1186/s12967-023-04283-4

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