Early IL-10 promotes vasculature-associated CD4+ T cells unable to control Mycobacterium tuberculosis infection
Cytokine-producing CD4+ T cells play a crucial role in the control of Mycobacterium tuberculosis infection; however, there is a delayed appearance of effector T cells in the lungs following aerosol infection. The immunomodulatory cytokine IL-10 antagonizes control of M. tuberculosis infection throug...
Auteurs principaux: | , , , , , , , , , |
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Format: | Article |
Langue: | English |
Publié: |
American Society for Clinical investigation
2021-11-01
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Collection: | JCI Insight |
Sujets: | |
Accès en ligne: | https://doi.org/10.1172/jci.insight.150060 |