Experience of early-life pain in premature infants is associated with atypical cerebellar development and later neurodevelopmental deficits

Experience of early-life pain in premature infants is associated with atypical cerebellar development and later neurodevelopmental deficits

Abstract Background Infants born very and extremely premature (V/EPT) are at a significantly elevated risk for neurodevelopmental disorders and delays even in the absence of structural brain injuries. These risks may be due to earlier-than-typical exposure to the extrauterine environment, and its br...

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Bibliographic Details
Main Authors: Kevin M. Cook, Josepheen De Asis-Cruz, Jung-Hoon Kim, Sudeepta K. Basu, Nickie Andescavage, Jonathan Murnick, Emma Spoehr, Melissa Liggett, Adré J. du Plessis, Catherine Limperopoulos
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Medicine
Subjects:
Early-life pain
fMRI
Brain development
Cerebellum
Prematurity
Neonatal intensive care unit
Online Access:https://doi.org/10.1186/s12916-023-03141-w

Internet

https://doi.org/10.1186/s12916-023-03141-w

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