A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development.

Survival of M. tuberculosis in host macrophages requires the eukaryotic-type protein kinase G, PknG, but the underlying mechanism has remained unknown. Here, we show that PknG is an integral component of a novel redox homeostatic system, RHOCS, which includes the ribosomal protein L13 and RenU, a Nu...

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Bibliographic Details
Main Authors: Kerstin A Wolff, Andres H de la Peña, Hoa T Nguyen, Thanh H Pham, L Mario Amzel, Sandra B Gabelli, Liem Nguyen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4401782?pdf=render