Limited Correlation between SARS-CoV-2 Serologic Assays for Identification of High-Titer COVID-19 Convalescent Plasma Using FDA Thresholds

Limited Correlation between SARS-CoV-2 Serologic Assays for Identification of High-Titer COVID-19 Convalescent Plasma Using FDA Thresholds

ABSTRACT In August 2020, the Food and Drug Administration (FDA) Emergency Use Authorization (EUA) for COVID-19 convalescent plasma (CCP) specified 12 authorized serologic assays and associated assay-specific cutoff values for the selection of high-titer CCP for use in hospitalized patients. The crit...

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Bibliographic Details
Main Authors: Nicholas E. Larkey, Radwa Ewaisha, Michael A. Lasho, Matthew M. Roforth, Dane Granger, Calvin R. Jerde, Liang Wu, Amy Gorsh, Stephen A. Klassen, Jonathon W. Senefeld, Michael J. Joyner, Nikola A. Baumann, Elitza S. Theel, John R. Mills
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
COVID-19 convalescent plasma
SARS-CoV-2
serology
antibody
CCP
FDA EUA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01154-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01154-22

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