Glucose-regulated protein 78 (Grp78) confers chemoresistance to tumor endothelial cells under acidic stress.
This study was designed to investigate the activation of the unfolded protein response (UPR) in tumor associated endothelial cells (TECs) and its association with chemoresistance during acidic pH stress.Endothelial cells from human oral squamous cell carcinomas (OSCC) were excised by laser capture m...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4071032?pdf=render |