Light-dependent regulation of neurotransmitter release from rod photoreceptor ribbon synapses involves an interplay of Complexin 4 and Transducin with the SNARE complex

Light-dependent regulation of neurotransmitter release from rod photoreceptor ribbon synapses involves an interplay of Complexin 4 and Transducin with the SNARE complex

Adaptation of photoreceptor sensitivity to varying light intensities is a fundamental requirement for retinal function and vision. Adaptive mechanisms in signal transduction are well described, but little is known about the mechanisms that adapt the photoreceptor synapse to changing light intensitie...

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Bibliographic Details
Main Authors: Uwe Thorsten Lux, Jutta Meyer, Olaf Jahn, Adam Davison, Norbert Babai, Andreas Gießl, Anna Wartenberg, Heinrich Sticht, Nils Brose, Kerstin Reim, Johann Helmut Brandstätter
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
mouse retina
G protein
ribbon synapses
neurotransmitter release
rod photoreceptor
light adaptation
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1308466/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1308466/full

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