Adjuvant trastuzumab and vinorelbine for early-stage HER2+ breast cancer

Background: The single-arm phase II APT trial established trastuzumab and paclitaxel (TH) as the standard adjuvant regimen for small human epidermal growth factor receptor 2 (HER2+) tumors. However, paclitaxel causes alopecia and has high rates of neuropathy and hypersensitivity reactions. In patien...

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Bibliographic Details
Main Authors: Shannon McLaughlin, Erika Nakajima, Yael Bar, Jennifer A. Hutchinson, Jennifer Shin, Beverly Moy, Steven J. Isakoff, Aditya Bardia, Irene Kuter, Laura M. Spring
Format: Article
Language:English
Published: SAGE Publishing 2023-01-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359221146133