A Mouse Model for Infection with Enterovirus A71 in Small Extracellular Vesicles

A Mouse Model for Infection with Enterovirus A71 in Small Extracellular Vesicles

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ABSTRACT Enterovirus A71 (EV-A71) is the major pathogen of hand, foot, and mouth disease (HFMD); in some severe cases, it could develop into central nervous system (CNS) disease such as aseptic meningitis, encephalitis, and neurogenic pulmonary edema in children under 5 years. The EV-A71 pathogenesi...

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Bibliographic Details
Main Authors: Jiaqi Gu, Jing Wu, Yuwen Cao, Xinran Zou, Xiaonan Jia, Yiqian Yin, Li Shen, Daihua Fang, Lingxiang Mao
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSphere
Subjects:
enterovirus A71 (EV-A71)
mouse model
small extracellular vesicles (sEVs)
central nervous system (CNS)
pathogenesis
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00377-20

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https://journals.asm.org/doi/10.1128/mSphere.00377-20

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