Mycophenolic Acid Synergizing with Lipopolysaccharide to Induce Interleukin-1β Release via Activation of Caspase-1

Mycophenolic Acid Synergizing with Lipopolysaccharide to Induce Interleukin-1β Release via Activation of Caspase-1

Background: The previous study showed that mycophenolic acid (MPA) synergizing with lipopolysaccharide (LPS) promoted interleukin (IL)-1β release, but the mechanism is unclear. This study aimed to investigate the mechanism of MPA synergizing with LPS to induce IL-1β release. Methods: Undiluted human...

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Bibliographic Details
Main Authors: Xue-Chan Huang, Yi He, Jian Zhuang, Juan He, Gui-Hu Luo, Jiao-Chan Han, Er-Wei Sun
Format: Article
Language:English
Published: Wolters Kluwer 2018-01-01
Series:Chinese Medical Journal
Subjects:
Autoimmune Diseases; Caspase-1 Host Defense; Interleukin-1β; Lipopolysaccharide Mycophenolic Acid
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=13;spage=1533;epage=1540;aulast=Huang

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http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=13;spage=1533;epage=1540;aulast=Huang

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